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The Placenta—A New Source of Bile Acids during Healthy Pregnancy? First Results of a Gene Expression Study in Humans and Mice

Bile acids (BAs) are natural ligands for several receptors modulating cell activities. BAs are synthesized via the classic (neutral) and alternative (acidic) pathways. The classic pathway is initiated by CYP7A1/Cyp7a1, converting cholesterol to 7α-hydroxycholesterol, while the alternative pathway st...

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Detalles Bibliográficos
Autores principales: Ontsouka, Edgar, Schroeder, Mariana, Ok, Linda, Vaillancourt, Cathy, Stroka, Deborah, Albrecht, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253767/
https://www.ncbi.nlm.nih.gov/pubmed/37298459
http://dx.doi.org/10.3390/ijms24119511