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Oncogenic Impact of TONSL, a Homologous Recombination Repair Protein at the Replication Fork, in Cancer Stem Cells

We investigated the role of TONSL, a mediator of homologous recombination repair (HRR), in stalled replication fork double-strand breaks (DSBs) in cancer. Publicly available clinical data (tumors from the ovary, breast, stomach and lung) were analyzed through KM Plotter, cBioPortal and Qomics. Cance...

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Detalles Bibliográficos
Autores principales: Lee, Hani, Ha, Sojung, Choi, SeokGyeong, Do, Soomin, Yoon, Sukjoon, Kim, Yong Kee, Kim, Woo-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253825/
https://www.ncbi.nlm.nih.gov/pubmed/37298484
http://dx.doi.org/10.3390/ijms24119530