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Plakophilin-3 Binds the Membrane and Filamentous Actin without Bundling F-Actin

Plakophilin-3 is a ubiquitously expressed protein found widely in epithelial cells and is a critical component of desmosomes. The plakophilin-3 carboxy-terminal domain harbors nine armadillo repeat motifs with largely unknown functions. Here, we report the 5 Å cryogenic electron microscopy (cryoEM)...

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Detalles Bibliográficos
Autores principales: Gupta, Jyoti, Rangarajan, Erumbi S., Troyanovsky, Regina B., Indra, Indrajyoti, Troyanovsky, Sergey M., Izard, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253835/
https://www.ncbi.nlm.nih.gov/pubmed/37298410
http://dx.doi.org/10.3390/ijms24119458