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CD11b Deficiency Favors Cartilage Calcification via Increased Matrix Vesicles, Apoptosis, and Lysyl Oxidase Activity

Pathological cartilage calcification is a hallmark feature of osteoarthritis, a common degenerative joint disease, characterized by cartilage damage, progressively causing pain and loss of movement. The integrin subunit CD11b was shown to play a protective role against cartilage calcification in a m...

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Detalles Bibliográficos
Autores principales: Bernabei, Ilaria, Hansen, Uwe, Ehirchiou, Driss, Brinckmann, Jürgen, Chobaz, Veronique, Busso, Nathalie, Nasi, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253935/
https://www.ncbi.nlm.nih.gov/pubmed/37298730
http://dx.doi.org/10.3390/ijms24119776