Cargando…
CD11b Deficiency Favors Cartilage Calcification via Increased Matrix Vesicles, Apoptosis, and Lysyl Oxidase Activity
Pathological cartilage calcification is a hallmark feature of osteoarthritis, a common degenerative joint disease, characterized by cartilage damage, progressively causing pain and loss of movement. The integrin subunit CD11b was shown to play a protective role against cartilage calcification in a m...
Autores principales: | Bernabei, Ilaria, Hansen, Uwe, Ehirchiou, Driss, Brinckmann, Jürgen, Chobaz, Veronique, Busso, Nathalie, Nasi, Sonia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253935/ https://www.ncbi.nlm.nih.gov/pubmed/37298730 http://dx.doi.org/10.3390/ijms24119776 |
Ejemplares similares
-
Xanthine Oxidoreductase Is Involved in Chondrocyte Mineralization and Expressed in Osteoarthritic Damaged Cartilage
por: Nasi, Sonia, et al.
Publicado: (2021) -
Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth
por: Kusano, Teruo, et al.
Publicado: (2019) -
CD11b Signaling Prevents Chondrocyte Mineralization and Attenuates the Severity of Osteoarthritis
por: Ehirchiou, Driss, et al.
Publicado: (2020) -
The Gasotransmitter Hydrogen Sulfide (H(2)S) Prevents Pathologic Calcification (PC) in Cartilage
por: Nasi, Sonia, et al.
Publicado: (2021) -
Fibrin deposition associates with cartilage degeneration in arthritis
por: Hügle, Thomas, et al.
Publicado: (2022)