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Skeletal Muscle-Specific Bis Depletion Leads to Muscle Dysfunction and Early Death Accompanied by Impairment in Protein Quality Control

Bcl-2-interacting cell death suppressor (BIS), also called BAG3, plays a role in physiological functions such as anti-apoptosis, cell proliferation, autophagy, and senescence. Whole-body Bis-knockout (KO) mice exhibit early lethality accompanied by abnormalities in cardiac and skeletal muscles, sugg...

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Detalles Bibliográficos
Autores principales: Jung, Soon-Young, Riew, Tae-Ryong, Yun, Hye Hyeon, Lim, Ji Hee, Hwang, Ji-Won, Jung, Sung Won, Kim, Hong Lim, Lee, Jae-Seon, Lee, Mun-Yong, Lee, Jeong-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253936/
https://www.ncbi.nlm.nih.gov/pubmed/37298584
http://dx.doi.org/10.3390/ijms24119635