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E7050 Suppresses the Growth of Multidrug-Resistant Human Uterine Sarcoma by Inhibiting Angiogenesis via Targeting of VEGFR2-Mediated Signaling Pathways

E7050 is an inhibitor of VEGFR2 with anti-tumor activity; however, its therapeutic mechanism remains incompletely understood. In the present study, we aim to evaluate the anti-angiogenic activity of E7050 in vitro and in vivo and define the underlying molecular mechanism. It was observed that treatm...

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Detalles Bibliográficos
Autores principales: Huang, Tsung-Teng, Chen, Chuan-Mu, Lin, Song-Shu, Lan, Ying-Wei, Cheng, Hsu-Chen, Choo, Kong-Bung, Wang, Ching-Chiung, Huang, Tse-Hung, Chong, Kowit-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253979/
https://www.ncbi.nlm.nih.gov/pubmed/37298555
http://dx.doi.org/10.3390/ijms24119606