Diastereoselective Synthesis of the Borylated d-Galactose Monosaccharide 3-Boronic-3-Deoxy-d-Galactose and Biological Evaluation in Glycosidase Inhibition and in Cancer for Boron Neutron Capture Therapy (BNCT)

Drug leads with a high Fsp(3) index are more likely to possess desirable properties for progression in the drug development pipeline. This paper describes the development of an efficient two-step protocol to completely diastereoselectively access a diethanolamine (DEA) boronate ester derivative of m...

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Detalles Bibliográficos
Autor principal: Simone, Michela I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254170/
https://www.ncbi.nlm.nih.gov/pubmed/37298796
http://dx.doi.org/10.3390/molecules28114321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254170/
https://www.ncbi.nlm.nih.gov/pubmed/37298796
http://dx.doi.org/10.3390/molecules28114321

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