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Single Cell Determination of 7,8-dihydro-8-oxo-2′-deoxyguanosine by Fluorescence Techniques: Antibody vs. Avidin Labeling

An important biomarker of oxidative damage in cellular DNA is the formation of 7,8-dihydro-8-oxo-2′-deoxyguanosine (8-oxodG). Although several methods are available for the biochemical analysis of this molecule, its determination at the single cell level may provide significant advantages when inves...

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Detalles Bibliográficos
Autores principales: Maraventano, Giusy, Ticli, Giulio, Cazzalini, Ornella, Stivala, Lucia A., Ramos-Gonzalez, Mariella, Rodríguez, José-Luis, Prosperi, Ennio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254197/
https://www.ncbi.nlm.nih.gov/pubmed/37298802
http://dx.doi.org/10.3390/molecules28114326