Design, Synthesis, and Anti-Cervical Cancer and Reversal of Tumor Multidrug Resistance Activity of Novel Nitrogen-Containing Heterocyclic Chalcone Derivatives

This study involved the design and synthesis of 21 new nitrogen-containing heterocyclic chalcone derivatives utilizing the active substructure splicing principle, with glycyrrhiza chalcone serving as the lead compound. The targets of these derivatives were VEGFR-2 and P-gp, and their efficacy agains...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Zheng, Liu, Zheng-Ye, Ablise, Mourboul, Maimaiti, Aikebaier, Mutalipu, Zuohelaguli, Alimujiang, Yusupuwajimu, Aihaiti, Aizitiaili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254235/
https://www.ncbi.nlm.nih.gov/pubmed/37299013
http://dx.doi.org/10.3390/molecules28114537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254235/
https://www.ncbi.nlm.nih.gov/pubmed/37299013
http://dx.doi.org/10.3390/molecules28114537

Ejemplares similares