Piplartine-Inspired 3,4,5-Trimethoxycinnamates: Trypanocidal, Mechanism of Action, and In Silico Evaluation

Chagas disease (CD) is one of the main neglected tropical diseases that promote relevant socioeconomic impacts in several countries. The therapeutic options for the treatment of CD are limited, and parasite resistance has been reported. Piplartine is a phenylpropanoid imide that has diverse biologic...

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Detalles Bibliográficos
Autores principales: Filho, Carlos S. M. B., de Menezes, Ramon R. P. P. B., Magalhães, Emanuel P., Castillo, Yunierkis P., Martins, Alice M. C., de Sousa, Damião P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254306/
https://www.ncbi.nlm.nih.gov/pubmed/37298988
http://dx.doi.org/10.3390/molecules28114512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254306/
https://www.ncbi.nlm.nih.gov/pubmed/37298988
http://dx.doi.org/10.3390/molecules28114512

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