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Piplartine-Inspired 3,4,5-Trimethoxycinnamates: Trypanocidal, Mechanism of Action, and In Silico Evaluation
Chagas disease (CD) is one of the main neglected tropical diseases that promote relevant socioeconomic impacts in several countries. The therapeutic options for the treatment of CD are limited, and parasite resistance has been reported. Piplartine is a phenylpropanoid imide that has diverse biologic...
Autores principales: | Filho, Carlos S. M. B., de Menezes, Ramon R. P. P. B., Magalhães, Emanuel P., Castillo, Yunierkis P., Martins, Alice M. C., de Sousa, Damião P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254306/ https://www.ncbi.nlm.nih.gov/pubmed/37298988 http://dx.doi.org/10.3390/molecules28114512 |
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