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Insights into the Structural Conformations of the Tau Protein in Different Aggregation Status

Tau is a protein characterized by large structural portions displaying extended conformational changes. Unfortunately, the accumulation of this protein into toxic aggregates in neuronal cells leads to a number of severe pathologies, collectively named tauopathies. In the last decade, significant res...

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Detalles Bibliográficos
Autores principales: Pinzi, Luca, Bisi, Nicolò, Sorbi, Claudia, Franchini, Silvia, Tonali, Nicolò, Rastelli, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254443/
https://www.ncbi.nlm.nih.gov/pubmed/37299020
http://dx.doi.org/10.3390/molecules28114544