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Stretch-Induced Down-Regulation of HCN2 Suppresses Contractile Activity

Although hyperpolarization-activated and cyclic nucleotide-gated 2 channels (HCN2) are expressed in multiple cell types in the gut, the role of HCN2 in intestinal motility is poorly understood. HCN2 is down-regulated in intestinal smooth muscle in a rodent model of ileus. Thus, the purpose of this s...

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Detalles Bibliográficos
Autores principales: Kola, Job Baffin, Turarova, Botagoz, Csige, Dora, Sipos, Ádám, Varga, Luca, Gergely, Bence, Refai, Farah Al, Uray, Iván P., Docsa, Tibor, Uray, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254498/
https://www.ncbi.nlm.nih.gov/pubmed/37298834
http://dx.doi.org/10.3390/molecules28114359