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Protocol for a systematic review and meta-analysis of the diagnostic test accuracy of host and HPV DNA methylation in cervical cancer screening and management

INTRODUCTION: Human papillomavirus (HPV) is necessary but not sufficient for cervical cancer development. During cervical carcinogenesis, methylation levels increase across host and HPV DNA. DNA methylation has been proposed as a test to diagnose cervical intraepithelial neoplasia (CIN); we present...

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Detalles Bibliográficos
Autores principales: Bowden, Sarah J, Ellis, Laura Burney, Kalliala, Ilkka, Paraskevaidi, Maria, Tighe, Jack, Kechagias, Konstantinos S, Doulgeraki, Triada, Paraskevaidis, Evangelos, Arbyn, Marc, Flanagan, James, Veroniki, Areti, Kyrgiou, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254594/
https://www.ncbi.nlm.nih.gov/pubmed/37277222
http://dx.doi.org/10.1136/bmjopen-2022-071534