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Zeolitic Imidazolate Framework-8 (ZIF-8) as a Drug Delivery Vehicle for the Transport and Release of Telomerase Inhibitor BIBR 1532

Telomerase is constitutively overexpressed in the majority of human cancers and telomerase inhibition provides a promising broad-spectrum anticancer therapeutic strategy. BIBR 1532 is a well-known synthetic telomerase inhibitor that blocks the enzymatic activity of hTERT, the catalytic subunit of te...

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Detalles Bibliográficos
Autores principales: Zhang, Shunyu, Li, Jinxia, Yan, Liang, You, Yue, Zhao, Feng, Cheng, Jixing, Yang, Limin, Sun, Yanqi, Chang, Qingchao, Liu, Ru, Li, Yunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254680/
https://www.ncbi.nlm.nih.gov/pubmed/37299682
http://dx.doi.org/10.3390/nano13111779