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Zeolitic Imidazolate Framework-8 (ZIF-8) as a Drug Delivery Vehicle for the Transport and Release of Telomerase Inhibitor BIBR 1532
Telomerase is constitutively overexpressed in the majority of human cancers and telomerase inhibition provides a promising broad-spectrum anticancer therapeutic strategy. BIBR 1532 is a well-known synthetic telomerase inhibitor that blocks the enzymatic activity of hTERT, the catalytic subunit of te...
Autores principales: | Zhang, Shunyu, Li, Jinxia, Yan, Liang, You, Yue, Zhao, Feng, Cheng, Jixing, Yang, Limin, Sun, Yanqi, Chang, Qingchao, Liu, Ru, Li, Yunhui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254680/ https://www.ncbi.nlm.nih.gov/pubmed/37299682 http://dx.doi.org/10.3390/nano13111779 |
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