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Quantitation of Tissue Amyloid via Fluorescence Spectroscopy Using Controlled Concentrations of Thioflavin-S

Amyloids are misfolded proteins that aggregate into fibrillar structures, the accumulation of which is associated with the pathogenesis of many neurodegenerative diseases, such as Alzheimer’s disease (AD). Early, sensitive detection of these misfolded aggregates is of great interest to the field, as...

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Detalles Bibliográficos
Autores principales: MacKeigan, Tatiana P., Morgan, Megan L., Stys, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254724/
https://www.ncbi.nlm.nih.gov/pubmed/37298959
http://dx.doi.org/10.3390/molecules28114483