Cargando…
Quantitation of Tissue Amyloid via Fluorescence Spectroscopy Using Controlled Concentrations of Thioflavin-S
Amyloids are misfolded proteins that aggregate into fibrillar structures, the accumulation of which is associated with the pathogenesis of many neurodegenerative diseases, such as Alzheimer’s disease (AD). Early, sensitive detection of these misfolded aggregates is of great interest to the field, as...
Autores principales: | MacKeigan, Tatiana P., Morgan, Megan L., Stys, Peter K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254724/ https://www.ncbi.nlm.nih.gov/pubmed/37298959 http://dx.doi.org/10.3390/molecules28114483 |
Ejemplares similares
-
Dual-probe fluorescence spectroscopy for sensitive quantitation of Alzheimer’s amyloid pathology
por: Stepanchuk, Anastasiia A., et al.
Publicado: (2022) -
Thioflavin T fluoresces as excimer in highly concentrated aqueous solutions and as monomer being incorporated in amyloid fibrils
por: Sulatskaya, Anna I., et al.
Publicado: (2017) -
Investigation of α-Synuclein Amyloid Fibrils Using the Fluorescent Probe Thioflavin T
por: Sulatskaya, Anna I., et al.
Publicado: (2018) -
Thioflavin T as an amyloid dye: fibril quantification, optimal concentration and effect on aggregation
por: Xue, Christine, et al.
Publicado: (2017) -
Fluorescence Quantum Yield of Thioflavin T in Rigid Isotropic Solution and Incorporated into the Amyloid Fibrils
por: Sulatskaya, Anna I., et al.
Publicado: (2010)