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Effects of intensive lipid lowering compared with moderate-intensity lipid lowering on coronary atherosclerotic plaque phenotype and major adverse cardiovascular events in adults with low to intermediate 10-year ASCVD risk (ILLUMINATION study): protocol for a multicentre, open-label, blinded-endpoint, randomised controlled trial

INTRODUCTION: Current guidelines recommend moderate-intensity lipid lowering (low-density lipoprotein cholesterol, LDL-C of <2.6 mmol/L or 30%–49% reduction from the baseline) for patients with intermediate 10-year atherosclerotic cardiovascular disease (ASCVD) risk. The effects of intensive lipi...

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Detalles Bibliográficos
Autores principales: Zheng, Jianan, Hou, Zhihui, Yuan, Jinqing, Zhao, Xueyan, Wang, Yang, Li, Jia, Zhang, Wenjia, Dou, Kefei, Lu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254782/
https://www.ncbi.nlm.nih.gov/pubmed/37277217
http://dx.doi.org/10.1136/bmjopen-2022-070832