Multicentre, interventional, single-arm study protocol of telemonitored circadian rhythms and patient-reported outcomes for improving mFOLFIRINOX safety in patients with pancreatic cancer (MultiDom, NCT04263948)

INTRODUCTION: Circadian clocks regulate cellular proliferation and drug effects. Tolerability and/or efficacy of anticancer therapies have been improved by their administration according to circadian rhythms, while being predicted by circadian robustness. The combination of leucovorin, fluorouracil,...

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Detalles Bibliográficos
Autores principales: Bouchahda, Mohamed, Ulusakarya, Ayhan, Thirot-Bidault, Anne, Attari, Amal, Bossevot, Rachel, Tuligenga, Richard, Hammel, Pascal, Adam, René, Levi, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254807/
https://www.ncbi.nlm.nih.gov/pubmed/37286324
http://dx.doi.org/10.1136/bmjopen-2022-069973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254807/
https://www.ncbi.nlm.nih.gov/pubmed/37286324
http://dx.doi.org/10.1136/bmjopen-2022-069973

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