Discovery of New 2-Phenylamino-3-acyl-1,4-naphthoquinones as Inhibitors of Cancer Cells Proliferation: Searching for Intra-Cellular Targets Playing a Role in Cancer Cells Survival

A series of 2-phenylamino-3-acyl-1,4-naphtoquinones were evaluated regarding their in vitro antiproliferative activities using DU-145, MCF-7 and T24 cancer cells. Such activities were discussed in terms of molecular descriptors such as half-wave potentials, hydrophobicity and molar refractivity. Com...

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Detalles Bibliográficos
Autores principales: Benites, Julio, Valderrama, Jaime A., Contreras, Álvaro, Enríquez, Cinthya, Pino-Rios, Ricardo, Yáñez, Osvaldo, Buc Calderon, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254843/
https://www.ncbi.nlm.nih.gov/pubmed/37298798
http://dx.doi.org/10.3390/molecules28114323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254843/
https://www.ncbi.nlm.nih.gov/pubmed/37298798
http://dx.doi.org/10.3390/molecules28114323

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