Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model

BACKGROUND: Treatment of some blood cancers with T cells that express a chimeric antigen receptor (CAR) against CD19 have shown remarkable results. In contrast, CAR-T cell efficacy against solid tumors has been difficult to achieve. METHODS: To examine the potential of CAR-T cell treatments against...

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Detalles Bibliográficos
Autores principales: Ranoa, Diana Rose E, Sharma, Preeti, Schane, Claire P, Lewis, Amber N, Valdez, Edward, Marada, Venkata V V R, Hager, Marlies V, Montgomery, Will, Wolf, Steven P, Schreiber, Karin, Schreiber, Hans, Bailey, Keith, Fan, Timothy M, Hergenrother, Paul J, Roy, Edward J, Kranz, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255004/
https://www.ncbi.nlm.nih.gov/pubmed/37258040
http://dx.doi.org/10.1136/jitc-2022-006509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255004/
https://www.ncbi.nlm.nih.gov/pubmed/37258040
http://dx.doi.org/10.1136/jitc-2022-006509

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