Modulation of the Intestinal Barrier Integrity and Repair by Microbiota Extracellular Vesicles through the Differential Regulation of Trefoil Factor 3 in LS174T Goblet Cells

Trefoil factor 3 (TFF3) plays a key role in the maintenance and repair of intestinal mucosa. TFF3 expression is upregulated by the microbiota through TLR2. At the posttranscriptional level, TFF3 is downregulated by miR-7-5p. Reduced TFF3 levels have been detected in the damaged tissue of IBD patient...

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Detalles Bibliográficos
Autores principales: Olivo-Martínez, Yenifer, Bosch, Manel, Badia, Josefa, Baldomà, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255446/
https://www.ncbi.nlm.nih.gov/pubmed/37299399
http://dx.doi.org/10.3390/nu15112437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255446/
https://www.ncbi.nlm.nih.gov/pubmed/37299399
http://dx.doi.org/10.3390/nu15112437

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