Lysosomal Ca(2+) flux modulates automaticity in ventricular cardiomyocytes and correlates with arrhythmic risk

Automaticity involves Ca(2+) handling at the cell membrane and sarcoplasmic reticulum (SR). Abnormal or acquired automaticity is thought to initiate ventricular arrhythmias associated with myocardial ischemia. Ca(2+) flux from mitochondria can influence automaticity, and lysosomes also release Ca(2+...

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Detalles Bibliográficos
Autores principales: Xie, An, Kang, Gyeoung-Jin, Kim, Eun Ji, Feng, Feng, Givens, Sophie E, Ogle, Brenda M, Dudley, Samuel C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Biological, Health, and Medical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255768/
https://www.ncbi.nlm.nih.gov/pubmed/37303713
http://dx.doi.org/10.1093/pnasnexus/pgad174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255768/
https://www.ncbi.nlm.nih.gov/pubmed/37303713
http://dx.doi.org/10.1093/pnasnexus/pgad174

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