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Lysosomal Ca(2+) flux modulates automaticity in ventricular cardiomyocytes and correlates with arrhythmic risk
Automaticity involves Ca(2+) handling at the cell membrane and sarcoplasmic reticulum (SR). Abnormal or acquired automaticity is thought to initiate ventricular arrhythmias associated with myocardial ischemia. Ca(2+) flux from mitochondria can influence automaticity, and lysosomes also release Ca(2+...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255768/ https://www.ncbi.nlm.nih.gov/pubmed/37303713 http://dx.doi.org/10.1093/pnasnexus/pgad174 |