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Natural flavonoids disrupt bacterial iron homeostasis to potentiate colistin efficacy

In the face of the alarming rise in global antimicrobial resistance, only a handful of novel antibiotics have been developed in recent decades, necessitating innovations in therapeutic strategies to fill the void of antibiotic discovery. Here, we established a screening platform mimicking the host m...

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Detalles Bibliográficos
Autores principales: Zhong, Zi-xing, Zhou, Shuang, Liang, Yu-jiao, Wei, Yi-yang, Li, Yan, Long, Teng-fei, He, Qian, Li, Meng-yuan, Zhou, Yu-feng, Yu, Yang, Fang, Liang-xing, Liao, Xiao-ping, Kreiswirth, Barry N., Chen, Liang, Ren, Hao, Liu, Ya-hong, Sun, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256158/
https://www.ncbi.nlm.nih.gov/pubmed/37294761
http://dx.doi.org/10.1126/sciadv.adg4205