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Transcriptional signatures of heroin intake and relapse throughout the brain reward circuitry in male mice

Opioid use disorder (OUD) looms as one of the most severe medical crises facing society. More effective therapeutics will require a deeper understanding of molecular changes supporting drug-taking and relapse. Here, we develop a brain reward circuit-wide atlas of opioid-induced transcriptional regul...

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Detalles Bibliográficos
Autores principales: Browne, Caleb J., Futamura, Rita, Minier-Toribio, Angélica, Hicks, Emily M., Ramakrishnan, Aarthi, Martínez-Rivera, Freddyson J., Estill, Molly, Godino, Arthur, Parise, Eric M., Torres-Berrío, Angélica, Cunningham, Ashley M., Hamilton, Peter J., Walker, Deena M., Huckins, Laura M., Hurd, Yasmin L., Shen, Li, Nestler, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256172/
https://www.ncbi.nlm.nih.gov/pubmed/37294757
http://dx.doi.org/10.1126/sciadv.adg8558