Distorted neurocomputation by a small number of extra-large spines in psychiatric disorders

Human genetics strongly support the involvement of synaptopathy in psychiatric disorders. However, trans-scale causality linking synapse pathology to behavioral changes is lacking. To address this question, we examined the effects of synaptic inputs on dendrites, cells, and behaviors of mice with kn...

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Detalles Bibliográficos
Autores principales: Obi-Nagata, Kisho, Suzuki, Norimitsu, Miyake, Ryuhei, MacDonald, Matthew L., Fish, Kenneth N., Ozawa, Katsuya, Nagahama, Kenichiro, Okimura, Tsukasa, Tanaka, Shoji, Kano, Masanobu, Fukazawa, Yugo, Sweet, Robert A., Hayashi-Takagi, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256173/
https://www.ncbi.nlm.nih.gov/pubmed/37294752
http://dx.doi.org/10.1126/sciadv.ade5973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256173/
https://www.ncbi.nlm.nih.gov/pubmed/37294752
http://dx.doi.org/10.1126/sciadv.ade5973

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