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Distorted neurocomputation by a small number of extra-large spines in psychiatric disorders
Human genetics strongly support the involvement of synaptopathy in psychiatric disorders. However, trans-scale causality linking synapse pathology to behavioral changes is lacking. To address this question, we examined the effects of synaptic inputs on dendrites, cells, and behaviors of mice with kn...
Autores principales: | Obi-Nagata, Kisho, Suzuki, Norimitsu, Miyake, Ryuhei, MacDonald, Matthew L., Fish, Kenneth N., Ozawa, Katsuya, Nagahama, Kenichiro, Okimura, Tsukasa, Tanaka, Shoji, Kano, Masanobu, Fukazawa, Yugo, Sweet, Robert A., Hayashi-Takagi, Akiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256173/ https://www.ncbi.nlm.nih.gov/pubmed/37294752 http://dx.doi.org/10.1126/sciadv.ade5973 |
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