Genomes of the autonomous parvovirus minute virus of mice induce replication stress through RPA exhaustion

The oncolytic autonomous parvovirus Minute Virus of Mice (MVM) establishes infection in the nuclear environment by usurping host DNA damage signaling proteins in the vicinity of cellular DNA break sites. MVM replication induces a global cellular DNA Damage Response (DDR) that is dependent on signali...

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Detalles Bibliográficos
Autores principales: Haubold, MegAnn K., Aquino, Jessica N. Pita, Rubin, Sarah R., Jones, Isabella K., Larsen, Clairine I. S., Pham, Edward, Majumder, Kinjal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256180/
https://www.ncbi.nlm.nih.gov/pubmed/37253065
http://dx.doi.org/10.1371/journal.ppat.1011203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256180/
https://www.ncbi.nlm.nih.gov/pubmed/37253065
http://dx.doi.org/10.1371/journal.ppat.1011203

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