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Genomes of the autonomous parvovirus minute virus of mice induce replication stress through RPA exhaustion
The oncolytic autonomous parvovirus Minute Virus of Mice (MVM) establishes infection in the nuclear environment by usurping host DNA damage signaling proteins in the vicinity of cellular DNA break sites. MVM replication induces a global cellular DNA Damage Response (DDR) that is dependent on signali...
Autores principales: | Haubold, MegAnn K., Aquino, Jessica N. Pita, Rubin, Sarah R., Jones, Isabella K., Larsen, Clairine I. S., Pham, Edward, Majumder, Kinjal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256180/ https://www.ncbi.nlm.nih.gov/pubmed/37253065 http://dx.doi.org/10.1371/journal.ppat.1011203 |
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