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Amino acid sequence assignment from single molecule peptide sequencing data using a two-stage classifier

We present a machine learning-based interpretive framework (whatprot) for analyzing single molecule protein sequencing data produced by fluorosequencing, a recently developed proteomics technology that determines sparse amino acid sequences for many individual peptide molecules in a highly paralleli...

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Detalles Bibliográficos
Autores principales: Smith, Matthew Beauregard, Simpson, Zack Booth, Marcotte, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256185/
https://www.ncbi.nlm.nih.gov/pubmed/37253025
http://dx.doi.org/10.1371/journal.pcbi.1011157