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Amino acid sequence assignment from single molecule peptide sequencing data using a two-stage classifier
We present a machine learning-based interpretive framework (whatprot) for analyzing single molecule protein sequencing data produced by fluorosequencing, a recently developed proteomics technology that determines sparse amino acid sequences for many individual peptide molecules in a highly paralleli...
Autores principales: | Smith, Matthew Beauregard, Simpson, Zack Booth, Marcotte, Edward M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256185/ https://www.ncbi.nlm.nih.gov/pubmed/37253025 http://dx.doi.org/10.1371/journal.pcbi.1011157 |
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