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Acyl ghrelin improves cardiac function in heart failure and increases fractional shortening in cardiomyocytes without calcium mobilization

BACKGROUND AND AIMS: Ghrelin is an endogenous appetite-stimulating peptide hormone with potential cardiovascular benefits. Effects of acylated (activated) ghrelin were assessed in patients with heart failure and reduced ejection fraction (HFrEF) and in ex vivo mouse cardiomyocytes. METHODS AND RESUL...

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Detalles Bibliográficos
Autores principales: Lund, Lars H, Hage, Camilla, Pironti, Gianluigi, Thorvaldsen, Tonje, Ljung-Faxén, Ulrika, Zabarovskaja, Stanislava, Shahgaldi, Kambiz, Webb, Dominic-Luc, Hellström, Per M, Andersson, Daniel C, Ståhlberg, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256198/
https://www.ncbi.nlm.nih.gov/pubmed/36916707
http://dx.doi.org/10.1093/eurheartj/ehad100