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High-sensitivity calcium biosensor on the mitochondrial surface reveals that IP3R channels participate in the reticular Ca(2+) leak towards mitochondria

Genetically encoded biosensors based on fluorescent proteins (FPs) are widely used to monitor dynamics and sub-cellular spatial distribution of calcium ion (Ca(2+)) fluxes and their role in intracellular signaling pathways. The development of different mutations in the Ca(2+)-sensitive elements of t...

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Detalles Bibliográficos
Autores principales: Gouriou, Yves, Gonnot, Fabrice, Wehbi, Mariam, Brun, Camille, Gomez, Ludovic, Bidaux, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256219/
https://www.ncbi.nlm.nih.gov/pubmed/37294746
http://dx.doi.org/10.1371/journal.pone.0285670