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Mutation rate, selection, and epistasis inferred from RNA virus haplotypes via neural posterior estimation
RNA viruses are particularly notorious for their high levels of genetic diversity, which is generated through the forces of mutation and natural selection. However, disentangling these two forces is a considerable challenge, and this may lead to widely divergent estimates of viral mutation rates, as...
Autores principales: | Caspi, Itamar, Meir, Moran, Ben Nun, Nadav, Abu Rass, Reem, Yakhini, Uri, Stern, Adi, Ram, Yoav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256221/ https://www.ncbi.nlm.nih.gov/pubmed/37305706 http://dx.doi.org/10.1093/ve/vead033 |
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