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Unraveling Heterogeneity in the Aging Hematopoietic Stem Cell Compartment: An Insight From Single-cell Approaches

Specific cell types and, therefore, organs respond differently during aging. This is also true for the hematopoietic system, where it has been demonstrated that hematopoietic stem cells alter a variety of features, such as their metabolism, and accumulate DNA damage, which can lead to clonal outgrow...

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Detalles Bibliográficos
Autores principales: Yang, Fei, Nourse, Craig, Helgason, G. Vignir, Kirschner, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256339/
https://www.ncbi.nlm.nih.gov/pubmed/37304939
http://dx.doi.org/10.1097/HS9.0000000000000895