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Anti-GD2 Antibody Dinutuximab Beta and Low-Dose Interleukin 2 After Haploidentical Stem-Cell Transplantation in Patients With Relapsed Neuroblastoma: A Multicenter, Phase I/II Trial

Patients with relapsed high-risk neuroblastoma (rHR-NB) have a poor prognosis. We hypothesized that graft-versus-neuroblastoma effects could be elicited by transplantation of haploidentical stem cells (haplo-SCT) exploiting cytotoxic functions of natural killer cells and their activation by the anti...

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Detalles Bibliográficos
Autores principales: Flaadt, Tim, Ladenstein, Ruth L., Ebinger, Martin, Lode, Holger N., Arnardóttir, Helga Björk, Poetschger, Ulrike, Schwinger, Wolfgang, Meisel, Roland, Schuster, Friedhelm R., Döring, Michaela, Ambros, Peter F., Queudeville, Manon, Fuchs, Jörg, Warmann, Steven W., Schäfer, Jürgen, Seitz, Christian, Schlegel, Patrick, Brecht, Ines B., Holzer, Ursula, Feuchtinger, Tobias, Simon, Thorsten, Schulte, Johannes H., Eggert, Angelika, Teltschik, Heiko-Manuel, Illhardt, Toni, Handgretinger, Rupert, Lang, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256422/
https://www.ncbi.nlm.nih.gov/pubmed/36854071
http://dx.doi.org/10.1200/JCO.22.01630