A complete graph-based approach with multi-task learning for predicting synergistic drug combinations

MOTIVATION: Drug combination therapy shows significant advantages over monotherapy in cancer treatment. Since the combinational space is difficult to be traversed experimentally, identifying novel synergistic drug combinations based on computational methods has become a powerful tool for pre-screeni...

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Detalles Bibliográficos
Autores principales: Wang, Xiaowen, Zhu, Hongming, Chen, Danyi, Yu, Yongsheng, Liu, Qi, Liu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256571/
https://www.ncbi.nlm.nih.gov/pubmed/37261842
http://dx.doi.org/10.1093/bioinformatics/btad351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256571/
https://www.ncbi.nlm.nih.gov/pubmed/37261842
http://dx.doi.org/10.1093/bioinformatics/btad351

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