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EZH2-Myc driven glioblastoma elicited by cytomegalovirus infection of human astrocytes

Mounting evidence is identifying human cytomegalovirus (HCMV) as a potential oncogenic virus. HCMV has been detected in malignant gliomas. EZH2 and Myc play a potential oncogenic role, correlating with the glioma grade. Herewith, we present the first experimental evidence for HCMV as a reprogramming...

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Detalles Bibliográficos
Autores principales: El Baba, Ranim, Pasquereau, Sébastien, Haidar Ahmad, Sandy, Monnien, Franck, Abad, Marine, Bibeau, Frédéric, Herbein, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256614/
https://www.ncbi.nlm.nih.gov/pubmed/37147437
http://dx.doi.org/10.1038/s41388-023-02709-3