GLP‑1 receptor agonist protects palmitate-induced insulin resistance in skeletal muscle cells by up-regulating sestrin2 to promote autophagy

In this study, we aimed to determine whether liraglutide could effectively reduce insulin resistance (IR) by regulating Sestrin2 (SESN2) expression in L6 rat skeletal muscle cells by examining its interactions with SESN2, autophagy, and IR. L6 cells were incubated with liraglutide (10–1000 nM) in th...

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Detalles Bibliográficos
Autores principales: Tian, Xue, Gao, Yu, Kong, Mowei, Zhao, Lihua, Xing, Enhong, Sun, Qitian, He, Jianqiu, Lu, Yanan, Feng, Zengbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256699/
https://www.ncbi.nlm.nih.gov/pubmed/37296162
http://dx.doi.org/10.1038/s41598-023-36602-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256699/
https://www.ncbi.nlm.nih.gov/pubmed/37296162
http://dx.doi.org/10.1038/s41598-023-36602-6

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