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Co-translational binding of importins to nascent proteins

Various cellular quality control mechanisms support proteostasis. While, ribosome-associated chaperones prevent the misfolding of nascent chains during translation, importins were shown to prevent the aggregation of specific cargoes in a post-translational mechanism prior the import into the nucleop...

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Detalles Bibliográficos
Autores principales: Seidel, Maximilian, Romanov, Natalie, Obarska-Kosinska, Agnieszka, Becker, Anja, Trevisan Doimo de Azevedo, Nayara, Provaznik, Jan, Nagaraja, Sankarshana R., Landry, Jonathan J. M., Benes, Vladimir, Beck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256725/
https://www.ncbi.nlm.nih.gov/pubmed/37296145
http://dx.doi.org/10.1038/s41467-023-39150-9