Cargando…

Co-translational binding of importins to nascent proteins

Various cellular quality control mechanisms support proteostasis. While, ribosome-associated chaperones prevent the misfolding of nascent chains during translation, importins were shown to prevent the aggregation of specific cargoes in a post-translational mechanism prior the import into the nucleop...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seidel, Maximilian, Romanov, Natalie, Obarska-Kosinska, Agnieszka, Becker, Anja, Trevisan Doimo de Azevedo, Nayara, Provaznik, Jan, Nagaraja, Sankarshana R., Landry, Jonathan J. M., Benes, Vladimir, Beck, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256725/ https://www.ncbi.nlm.nih.gov/pubmed/37296145 http://dx.doi.org/10.1038/s41467-023-39150-9

Ejemplares similares

Co-translational assembly orchestrates competing biogenesis pathways
por: Seidel, Maximilian, et al.
Publicado: (2022)

PepComposer: computational design of peptides binding to a given protein surface
por: Obarska-Kosinska, Agnieszka, et al.
Publicado: (2016)

Lack of Conserved miRNA Deregulation in HPV-Induced Squamous Cell Carcinomas
por: Nunvar, Jaroslav, et al.
Publicado: (2021)

Corrigendum to “HsdR Subunit of the Type I Restriction-Modification Enzyme EcoR124I: Biophysical Characterisation and Structural Modelling” [J. Mol. Biol. 376(2) 2008 Feb 15: 438–452.]()
por: Obarska-Kosinska, Agnieszka, et al.
Publicado: (2020)

Importins and exportins in cellular differentiation
por: Okada, Norihisa, et al.
Publicado: (2008)

Xenopus importin beta validates human importin beta as a cell cycle negative regulator
por: Delmar, Valerie A, et al.
Publicado: (2008)

Nuclear translation visualized by ribosome-bound nascent chain puromycylation
por: David, Alexandre, et al.
Publicado: (2012)

Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones
por: Pausch, Patrick, et al.
Publicado: (2015)

The molecular basis for the regulation of the CBC by the importins
por: Dias, Sandra M.G., et al.
Publicado: (2009)

Nascent SecM Chain Outside the Ribosome Reinforces Translation Arrest
por: Yang, Zhuohao, et al.
Publicado: (2015)

A Mutation Upstream of the rplN-rpsD Ribosomal Operon Downregulates Bordetella pertussis Virulence Factor Production without Compromising Bacterial Survival within Human Macrophages
por: Novák, Jakub, et al.
Publicado: (2020)

HsdR Subunit of the Type I Restriction-Modification Enzyme EcoR124I: Biophysical Characterisation and Structural Modelling
por: Obarska-Kosinska, Agnieszka, et al.
Publicado: (2008)

Ligand crowding at a nascent signal sequence
por: Eisner, Gottfried, et al.
Publicado: (2003)

Interactions between nascent proteins and the ribosome surface inhibit co-translational folding
por: Cassaignau, Anaïs M. E., et al.
Publicado: (2021)

Prediction of histone post-translational modification patterns based on nascent transcription data
por: Wang, Zhong, et al.
Publicado: (2022)

Immunoprecipitation of Reporter Nascent Chains from Active Ribosomes to Study Translation Efficiency
por: Cacioppo, Roberta, et al.
Publicado: (2023)

Nuclear importin α and its physiological importance
por: Miyamoto, Yoichi, et al.
Publicado: (2012)

Importin-beta-like nuclear transport receptors
por: Ström, Anne-Christine, et al.
Publicado: (2001)

Stimulated nuclear import by β-like importins
por: Flores, Karen, et al.
Publicado: (2013)

Importins and Exportins Regulating Allergic Immune Responses
por: Aggarwal, Ankita, et al.
Publicado: (2014)

The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP–importin α interactions
por: Jung, Hunmin, et al.
Publicado: (2020)

Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding
por: Kimura, Makoto, et al.
Publicado: (2021)

Conservation of Importin α Function in Apicomplexans: Ivermectin and GW5074 Target Plasmodium falciparum Importin α and Inhibit Parasite Growth in Culture
por: Walunj, Sujata B., et al.
Publicado: (2022)

A Possible Role of the Full-Length Nascent Protein in Post-Translational Ribosome Recycling
por: Das, Debasis, et al.
Publicado: (2017)

Non-equilibrium dynamics of a nascent polypeptide during translation suppress its misfolding
por: Alexander, Lisa M., et al.
Publicado: (2019)

Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain
por: Lintner, Nathanael G., et al.
Publicado: (2017)

Nascent SecM chain interacts with outer ribosomal surface to stabilize translation arrest
por: Muta, Mikihisa, et al.
Publicado: (2020)

miRNA-mediated loss of m(6)A increases nascent translation in glioblastoma
por: Zepecki, John P., et al.
Publicado: (2021)

A nascent peptide code for translational control of mRNA stability in human cells
por: Burke, Phillip C., et al.
Publicado: (2022)

Modeling post‐translational modifications and cancer‐associated mutations that impact the heterochromatin protein 1α‐importin α heterodimers
por: Zimmermann, Michael T., et al.
Publicado: (2019)

Increased expression of importin13 in endometriosis and endometrial carcinoma
por: Zeng, Biao, et al.
Publicado: (2012)

Increased importin 13 activity is associated with the pathogenesis of pterygium
por: Xu, Ke, et al.
Publicado: (2013)

An Importin Code in neuronal transport from synapse-to-nucleus?
por: Lever, Michael B., et al.
Publicado: (2015)

Data on dimer formation between importin α subtypes
por: Miyamoto, Yoichi, et al.
Publicado: (2016)

Importin-11 keeps PTEN safe from harm
por: Leslie, Nick R.
Publicado: (2017)

Importin-11 is Essential for Normal Embryonic Development in Mice
por: Lee, Ju-Young, et al.
Publicado: (2020)

Correction: Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain
por: Lintner, Nathanael G., et al.
Publicado: (2018)

Asc1, Hel2, and Slh1 couple translation arrest to nascent chain degradation
por: Sitron, Cole S., et al.
Publicado: (2017)

Operationalization, implementation, and evaluation of Collaboration Planning: A pilot interventional study of nascent translational teams
por: Rolland, Betsy, et al.
Publicado: (2020)

A nascent polypeptide sequence modulates DnaA translation elongation in response to nutrient availability
por: Felletti, Michele, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6gmi08mqhic3k3em5pumm8cqsf