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A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase

Dimethylarginine dimethylaminohydrolase 1 (DDAH1) protects against cardiovascular disease by metabolising the risk factor asymmetric dimethylarginine (ADMA). However, the question whether the second DDAH isoform, DDAH2, directly metabolises ADMA has remained unanswered. Consequently, it is still unc...

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Detalles Bibliográficos
Autores principales: Ragavan, Vinitha N., Nair, Pramod C., Jarzebska, Natalia, Angom, Ramcharan Singh, Ruta, Luana, Bianconi, Elisa, Grottelli, Silvia, Tararova, Natalia D., Ryazanskiy, Daniel, Lentz, Steven R., Tommasi, Sara, Martens-Lobenhoffer, Jens, Suzuki-Yamamoto, Toshiko, Kimoto, Masumi, Rubets, Elena, Chau, Sarah, Chen, Yingjie, Hu, Xinli, Bernhardt, Nadine, Spieth, Peter M., Weiss, Norbert, Bornstein, Stefan R., Mukhopadhyay, Debabrata, Bode-Böger, Stefanie M., Maas, Renke, Wang, Ying, Macchiarulo, Antonio, Mangoni, Arduino A., Cellini, Barbara, Rodionov, Roman N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256801/
https://www.ncbi.nlm.nih.gov/pubmed/37296100
http://dx.doi.org/10.1038/s41467-023-38467-9