A Cas3-base editing tool for targetable in vivo mutagenesis

The generation of genetic diversity via mutagenesis is routinely used for protein engineering and pathway optimization. Current technologies for random mutagenesis often target either the whole genome or relatively narrow windows. To bridge this gap, we developed CoMuTER (Confined Mutagenesis using...

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Detalles Bibliográficos
Autores principales: Zimmermann, Anna, Prieto-Vivas, Julian E., Cautereels, Charlotte, Gorkovskiy, Anton, Steensels, Jan, Van de Peer, Yves, Verstrepen, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256805/
https://www.ncbi.nlm.nih.gov/pubmed/37296137
http://dx.doi.org/10.1038/s41467-023-39087-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256805/
https://www.ncbi.nlm.nih.gov/pubmed/37296137
http://dx.doi.org/10.1038/s41467-023-39087-z

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