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A Cas3-base editing tool for targetable in vivo mutagenesis
The generation of genetic diversity via mutagenesis is routinely used for protein engineering and pathway optimization. Current technologies for random mutagenesis often target either the whole genome or relatively narrow windows. To bridge this gap, we developed CoMuTER (Confined Mutagenesis using...
Autores principales: | Zimmermann, Anna, Prieto-Vivas, Julian E., Cautereels, Charlotte, Gorkovskiy, Anton, Steensels, Jan, Van de Peer, Yves, Verstrepen, Kevin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256805/ https://www.ncbi.nlm.nih.gov/pubmed/37296137 http://dx.doi.org/10.1038/s41467-023-39087-z |
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