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Navoximod modulates local HSV-1 replication to reshape tumor immune microenvironment for enhanced immunotherapy via an injectable hydrogel

Oncolytic virotherapy can lead to tumor lysis and systemic anti-tumor immunity, but the therapeutic potential in humans is limited due to the impaired virus replication and the insufficient ability to overcome the immunosuppressive tumor microenvironment (TME). To solve the above problems, we identi...

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Detalles Bibliográficos
Autores principales: Zhuang, Qiuyu, Zhao, Binyu, Lin, Zhiwen, Liang, Yuzhi, Zhao, Qingfu, Wang, Yunhao, Liao, Naishun, Tu, Haibin, Zheng, Youshi, Chen, Hengkai, Zeng, Yongyi, Zhang, Da, Liu, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256817/
https://www.ncbi.nlm.nih.gov/pubmed/37296221
http://dx.doi.org/10.1038/s42003-023-04983-z