Splicing activates transcription from weak promoters upstream of alternative exons

Transcription and splicing are intrinsically coupled. Alternative splicing of internal exons can fine-tune gene expression through a recently described phenomenon called exon-mediated activation of transcription starts (EMATS). However, the association of this phenomenon with human diseases remains...

Descripción completa

Detalles Bibliográficos
Autores principales: Uriostegui-Arcos, Maritere, Mick, Steven T., Shi, Zhuo, Rahman, Rufuto, Fiszbein, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256964/
https://www.ncbi.nlm.nih.gov/pubmed/37301863
http://dx.doi.org/10.1038/s41467-023-39200-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256964/
https://www.ncbi.nlm.nih.gov/pubmed/37301863
http://dx.doi.org/10.1038/s41467-023-39200-2

Ejemplares similares