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Splicing activates transcription from weak promoters upstream of alternative exons

Transcription and splicing are intrinsically coupled. Alternative splicing of internal exons can fine-tune gene expression through a recently described phenomenon called exon-mediated activation of transcription starts (EMATS). However, the association of this phenomenon with human diseases remains...

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Detalles Bibliográficos
Autores principales:	Uriostegui-Arcos, Maritere, Mick, Steven T., Shi, Zhuo, Rahman, Rufuto, Fiszbein, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256964/ https://www.ncbi.nlm.nih.gov/pubmed/37301863 http://dx.doi.org/10.1038/s41467-023-39200-2

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